Was doing a routine check and noticed in the hijack this log, there were files "missing"....what does this mean? is there a problem?

Logfile of HijackThis v1.99.1
Scan saved at 5:08:52 PM, on 7/12/2010
Platform: Unknown Windows (WinNT 6.01.3504)
MSIE: Internet Explorer v8.00 (8.00.7600.16385)

Running processes:
C:\Program Files (x86)\Symantec\Symantec Endpoint Protection\ProtectionUtilSurrogate.exe
C:\Program Files\Alienware\Command Center\AlienFusionController.exe
C:\Program Files (x86)\Dell DataSafe Local Backup\Components\scheduler\STService.exe
C:\Program Files (x86)\Dell DataSafe Local Backup\Toaster.exe
C:\Program Files (x86)\Intel\Intel Matrix Storage Manager\IAAnotif.exe
C:\Program Files\Alienware\Command Center\AlienwareAlienFXController.exe
C:\Program Files (x86)\Skype\Phone\Skype.exe
C:\Program Files (x86)\Windows Live\Messenger\msnmsgr.exe
C:\ProgramData\MXSkypeRecorder\MXSkypeRecorder.exe
C:\Program Files\Alienware\Command Center\AlienSense\FATrayMon.exe
C:\Program Files (x86)\CyberLink\Shared Files\brs.exe
C:\Program Files (x86)\Common Files\Symantec Shared\ccApp.exe
C:\Program Files\Alienware\Command Center\AlienSense\FATrayAlert.exe
C:\Program Files\Alienware\Command Center\AlienFXHook32Mngr.exe
c:\Program Files\WIDCOMM\Bluetooth Software\BluetoothHeadsetProxy.exe
C:\Program Files (x86)\Skype\Plugin Manager\skypePM.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Users\Shawn\AppData\Local\Google\Chrome\Application\chrome.exe
C:\Program Files (x86)\Heroes of Newerth\hon.exe
C:\Program Files (x86)\Hijackthis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.alienware.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.alienware.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Local Page = C:\Windows\SysWOW64\blank.htm
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
F2 - REG:system.ini: UserInit=userinit.exe
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files (x86)\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: (no name) - {5C255C8A-E604-49b4-9D64-90988571CECB} - (no file)
O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\Program Files (x86)\Microsoft Office\Office12\GrooveShellExtensions.dll
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files (x86)\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: SkypeIEPluginBHO - {AE805869-2E5C-4ED4-8F7B-F1F7851A4497} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O2 - BHO: SSOIEAddonBHO - {DA5BCE70-D057-4D63-943D-5F3927EC59F1} - C:\Program Files\Alienware\Command Center\AlienSense\FAIESSO.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files (x86)\Java\jre6\bin\jp2ssv.dll
O3 - Toolbar: DAEMON Tools Toolbar - {32099AAC-C132-4136-9E9A-4E364A424E17} - C:\Program Files (x86)\DAEMON Tools Toolbar\DTToolbar.dll
O4 - HKLM\..\Run: [OSD_LAUNCH] c:\Program Files (x86)\OSD\Launch.exe
O4 - HKLM\..\Run: [FATrayAlert] C:\Program Files\Alienware\Command Center\AlienSense\FATrayMon.exe
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files (x86)\Adobe\Reader 9.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [BDRegion] c:\Program Files (x86)\Cyberlink\Shared Files\brs.exe
O4 - HKLM\..\Run: [UCam_Menu] "c:\Program Files (x86)\CyberLink\YouCam\MUITransfer\MUIStartMenu.exe" "c:\Program Files (x86)\CyberLink\YouCam" UpdateWithCreateOnce "Software\CyberLink\YouCam\2.0"
O4 - HKLM\..\Run: [ccApp] "C:\Program Files (x86)\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [GrooveMonitor] "C:\Program Files (x86)\Microsoft Office\Office12\GrooveMonitor.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files (x86)\Common Files\Java\Java Update\jusched.exe"
O4 - HKLM\..\RunOnce: [Launcher] C:\Program Files (x86)\Dell DataSafe Local Backup\Components\scheduler\Launcher.exe
O4 - HKLM\..\RunOnce: [STToasterLauncher] C:\Program Files (x86)\Dell DataSafe Local Backup\toasterLauncher.exe
O4 - HKCU\..\Run: [Skype] "C:\Program Files (x86)\Skype\Phone\Skype.exe" /nosplash /minimized
O4 - HKCU\..\Run: [Sidebar] C:\Program Files\Windows Sidebar\sidebar.exe /autoRun
O4 - HKCU\..\Run: [msnmsgr] "C:\Program Files (x86)\Windows Live\Messenger\msnmsgr.exe" /background
O4 - HKCU\..\Run: [Google Update] "C:\Users\Shawn\AppData\Local\Google\Update\GoogleUpdate.exe" /c
O4 - HKCU\..\Run: [MX Skype Recorder] "C:\ProgramData\MXSkypeRecorder\MXSkypeRecorder.exe" /autorun
O4 - Global Startup: AWMouseCI.lnk = C:\Program Files\Alienware\Alienware TactX Mouse CI\AWMouseCI.exe
O4 - Global Startup: Bluetooth.lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~2\MICROS~1\Office12\EXCEL.EXE/3000
O8 - Extra context menu item: Send image to &Bluetooth Device... - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm
O8 - Extra context menu item: Send page to &Bluetooth Device... - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~1\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~2\MICROS~1\Office12\ONBttnIE.dll
O9 - Extra button: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O9 - Extra 'Tools' menuitem: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~2\MICROS~1\Office12\REFIEBAR.DLL
O9 - Extra button: Send To Bluetooth - {CCA281CA-C863-46ef-9331-5C8D4460577F} - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra 'Tools' menuitem: Send to &Bluetooth Device... - {CCA281CA-C863-46ef-9331-5C8D4460577F} - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O10 - Unknown file in Winsock LSP: c:\windows\system32\nlaapi.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\napinsp.dll
O11 - Options group: [INTERNATIONAL] International
O13 - Gopher Prefix:
O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\Program Files (x86)\Microsoft Office\Office12\GrooveSystemServices.dll
O18 - Protocol: livecall - {828030A1-22C1-4009-854F-8E305202313F} - C:\PROGRA~2\WIC4A1~1\MESSEN~1\MSGRAP~1.DLL
O18 - Protocol: ms-help - {314111C7-A502-11D2-BBCA-00C04F8EC294} - C:\Program Files (x86)\Common Files\Microsoft Shared\Help\hxds.dll
O18 - Protocol: msnim - {828030A1-22C1-4009-854F-8E305202313F} - C:\PROGRA~2\WIC4A1~1\MESSEN~1\MSGRAP~1.DLL
O18 - Protocol: skype-ie-addon-data - {91774881-D725-4E58-B298-07617B9B86A8} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\Program Files (x86)\Skype Recorder\Skype4COM.dll
O18 - Filter hijack: text/xml - {807563E5-5146-11D5-A672-00B0D022E945} - C:\PROGRA~2\COMMON~1\MICROS~1\OFFICE12\MSOXMLMF.DLL
O20 - Winlogon Notify: FastAccess - C:\Program Files\Alienware\Command Center\AlienSense\FALogNot.dll
O23 - Service: Andrea ST Filters Service (AESTFilters) - Andrea Electronics Corporation - C:\Windows\System32\DriverStore\FileRepository\stwrt64.inf_amd64_neutral_056607ee0106e5e8\AESTSr64.exe
O23 - Service: @%SystemRoot%\system32\Alg.exe,-112 (ALG) - Unknown owner - C:\Windows\System32\alg.exe (file missing)
O23 - Service: Alienware Fusion Service (AlienFusionService) - Alienware - C:\Program Files\Alienware\Command Center\AlienFusionService.exe
O23 - Service: Bluetooth Service (btwdins) - Broadcom Corporation. - c:\Program Files\WIDCOMM\Bluetooth Software\btwdins.exe
O23 - Service: Symantec Event Manager (ccEvtMgr) - Unknown owner - C:\Program Files (x86)\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: Symantec Settings Manager (ccSetMgr) - Unknown owner - C:\Program Files (x86)\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: @%SystemRoot%\system32\efssvc.dll,-100 (EFS) - Unknown owner - C:\Windows\System32\lsass.exe (file missing)
O23 - Service: FAService - Sensible Vision - C:\Program Files\Alienware\Command Center\AlienSense\FAService.exe
O23 - Service: @%systemroot%\system32\fxsresm.dll,-118 (Fax) - Unknown owner - C:\Windows\system32\fxssvc.exe (file missing)
O23 - Service: HappyOSD - Unknown owner - C:\Program Files (x86)\OSD\OSD_Service.exe
O23 - Service: Intel(R) Matrix Storage Event Monitor (IAANTMON) - Intel Corporation - C:\Program Files (x86)\Intel\Intel Matrix Storage Manager\IAANTMon.exe
O23 - Service: @keyiso.dll,-100 (KeyIso) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: LiveUpdate - Symantec Corporation - C:\PROGRA~2\Symantec\LIVEUP~1\LUCOMS~1.EXE
O23 - Service: @comres.dll,-2797 (MSDTC) - Unknown owner - C:\Windows\System32\msdtc.exe (file missing)
O23 - Service: Nero BackItUp Scheduler 4.0 - Nero AG - C:\Program Files (x86)\Common Files\Nero\Nero BackItUp 4\NBService.exe
O23 - Service: @%SystemRoot%\System32\netlogon.dll,-102 (Netlogon) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: NVIDIA Display Driver Service (nvsvc) - Unknown owner - C:\Windows\system32\nvvsvc.exe (file missing)
O23 - Service: @%systemroot%\system32\psbase.dll,-300 (ProtectedStorage) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\qwave.dll,-1 (QWAVE) - Unknown owner - %windir%\system32\svchost.exe (file missing)
O23 - Service: @%systemroot%\system32\Locator.exe,-2 (RpcLocator) - Unknown owner - C:\Windows\system32\locator.exe (file missing)
O23 - Service: @%SystemRoot%\system32\samsrv.dll,-1 (SamSs) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\seclogon.dll,-7001 (seclogon) - Unknown owner - %windir%\system32\svchost.exe (file missing)
O23 - Service: SoftThinks Agent Service (SftService) - SoftThinks - C:\Program Files (x86)\Dell DataSafe Local Backup\sftservice.EXE
O23 - Service: Symantec Management Client (SmcService) - Symantec Corporation - C:\Program Files (x86)\Symantec\Symantec Endpoint Protection\Smc.exe
O23 - Service: @%SystemRoot%\system32\snmptrap.exe,-3 (SNMPTRAP) - Unknown owner - C:\Windows\System32\snmptrap.exe (file missing)
O23 - Service: @%systemroot%\system32\spoolsv.exe,-1 (Spooler) - Unknown owner - C:\Windows\System32\spoolsv.exe (file missing)
O23 - Service: @%SystemRoot%\system32\sppsvc.exe,-101 (sppsvc) - Unknown owner - C:\Windows\system32\sppsvc.exe (file missing)
O23 - Service: Audio Service (STacSV) - IDT, Inc. - C:\Windows\System32\DriverStore\FileRepository\stwrt64.inf_amd64_neutral_056607ee0106e5e8\STacSV64.exe
O23 - Service: Steam Client Service - Valve Corporation - C:\Program Files (x86)\Common Files\Steam\SteamService.exe
O23 - Service: Symantec Endpoint Protection (Symantec AntiVirus) - Symantec Corporation - C:\Program Files (x86)\Symantec\Symantec Endpoint Protection\Rtvscan.exe
O23 - Service: @%SystemRoot%\system32\ui0detect.exe,-101 (UI0Detect) - Unknown owner - C:\Windows\system32\UI0Detect.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vaultsvc.dll,-1003 (VaultSvc) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vds.exe,-100 (vds) - Unknown owner - C:\Windows\System32\vds.exe (file missing)
O23 - Service: @%systemroot%\system32\vssvc.exe,-102 (VSS) - Unknown owner - C:\Windows\system32\vssvc.exe (file missing)
O23 - Service: @%SystemRoot%\system32\Wat\WatUX.exe,-601 (WatAdminSvc) - Unknown owner - C:\Windows\system32\Wat\WatAdminSvc.exe (file missing)
O23 - Service: @%systemroot%\system32\wbengine.exe,-104 (wbengine) - Unknown owner - C:\Windows\system32\wbengine.exe (file missing)
O23 - Service: DW WLAN Tray Service (wltrysvc) - Unknown owner - C:\Program Files\Dell\DW WLAN Card\WLTRYSVC.EXE" "C:\Program Files\Dell\DW WLAN Card\bcmwltry.exe (file missing)
O23 - Service: @%Systemroot%\system32\wbem\wmiapsrv.exe,-110 (wmiApSrv) - Unknown owner - C:\Windows\system32\wbem\WmiApSrv.exe (file missing)
O23 - Service: @%PROGRAMFILES%\Windows Media Player\wmpnetwk.exe,-101 (WMPNetworkSvc) - Unknown owner - %PROGRAMFILES%\Windows Media Player\wmpnetwk.exe (file missing)

Hello and welcome.

That's normal, HijackThis cannot 'see' those files, but they're there in most cases, excluding the O2 BHO section, those are either incomplete uinstalls or broken installs. You can fix those, but leave all the others